antiparkinsonism drugs

 

Drug used in Parkinsonism / antiparkinsonism

1. Drug that increase dopamine level

a. Dopamine precursor

Levodopa - given with carbidopa and benserazide

b. Dopaminergic agonist

Bromocryptine

c. Inhibit dopamine metabolism

Selegiline

Tolcapone

Entacapone

d. Dopamine releasing drug

Amantadine

2. Drug reduce cholinergic system; anticholinergic drug

1. Central anticholinergic

Benztropine

Benzhexol

Trihexyphenidyl 

2. Antihistamines

Diphenhydramine

Promethazine

Drug induced Parkinsonism

Reserpine

Metoclopramide

Phenothiazines