Antimalarial Drugs

 Antimalarial Drug

Classification of antimalarials drug

1. Causal prophylactic (primary tissue schizontocides)

(Destroy parasite in liver cells and prevent invasion of Erythrocytes)

Primaquine 

Pyrimethamine (folate antagonists)

2. (Suppressive form) Blood schizontocides (destroy parasite in RBC and terminal clinical attacks of malaria)

Chloroquine

Quinine

Mefoquine

Halofantrine

Hydroxychloroquinine

Pyrimethamine

Chloroguanide

Artemisinin

3. Tissue schizontocides (act on hypnozoites of P. vivax and P. ovale that reproduce relapse)

Primaquine (Hypnozoitocidal drug)

4. Gametocidal Drug (destroy gametocytes and prevent transmission)

Primaquine

Chloroquine

Quinin