Drugs used in endocrine disorders

 1. Insulin and oral Hypoglycemics

Insuline

Types of insulin 

1. Rapid acting insulin

a. Insulin lispro

b. Insulin aspart

c. Insulin glulisine

2. Short - acting insulin

Regular insulin 

3. Intermediate acting insulin

a. Insulin zinc suspension

b. Neutral protamine hagedorn (NPH) or

c. Isophane insulin (NPH)

4. Long acting insulin 

a. Protamine zinc insulin (PZI)

b. Insulin glargine

2. Oral Hypoglycemic drugs/ oral antidiabetic drugs

Classification

1. Drug that increase insulin secretion

a. Sulfonylureas

First generation drug;

Tolbutamide

Tolazamide

Second generation drug

Glipizide

Glimepiride 

b. Meglitinides 

Repaglinide

Nateglinide

2. Biguanides

Metformin

Phenformin

3. Thiazolidinediones (TZDs)

Pioglitazone

4. Alpha glucosidase inhibitors

Acarbose

Miglitol

5. Newer drugs

a. Amylin Analog

Pramlintide

b. GLP-1 analogue(glucagon like peptide)

Liraglutide

c. DPP-4 inhibitors (dipeptidyl peptidase- 4 inhibitors)

Sitagliptin

d. SGLT- 2 inhibitors; sodium-glucose cotransporter-2 inhibitors

Remogliflozin