Mycoplasma Pneumoniae
These are Pleomorphic gram negative pathogenic bacilli.
Mycoplasma Pneumoniae cause respiratory tract infection (respiratory fluids).
Morphology
Mycoplasma Pneumoniae is very small bacterium.
Non- sporing and usually non- motile.
Due to absence of cell wall can change their shape.
Characteristics
Optimum temperature for growth is 35-37 degree Celsius.
Multiply by binary fission or division.
Source and Mode of Transmission
Mycoplasma Pneumoniae is transmitted by respiratory droplets.
Nasopharyngeal secretion through contaminated dust particles.
Direct contact with patient.
Inhalation of contaminated droplets.
Pathogenesis
Mycoplasma Pneumoniae cause lower respiratory tract infection called primarily atypical Pneumonia.
Cause headache, fever, chills, malaise
Infection with mycoplasma pneumoniae evoke both local and systemic immune respiratory.
Laboratory Diagnosis
Specimen collection
Sputum, throat swab, blood sample
Microscope examination
Cultural characteristics and culture
Facultative anaerobic and aerobic grow optimum temperature 35-37 degree Celsius.
Biochemical test
Utilize glucose as main source of energy.
Serological tests
a. Complement fixation test
b. Cold agglutination test
c. PCR in case of respiratory secretion help of detect specific DNA of Mycoplasma Pneumoniae.
Treatment
Tetracyclines and erythromycins, doxycycline are antibiotics used for treatment mycoplasma Pneumoniae infection.
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