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Components of Connective Tissue - Matrix, Connective Tissue Cell

Connective tissue is a group of tissues that connect other tissues together and provide cohesion, internal support and maintain the form of the body and its organs.

 

Check out here types of connective tissue.

 

Components of Connective Tissue    

 

1. Matrix; material between cells


2. Connective tissue cell

 

Know here the function of connective tissue.

 

1.  Matrix

 

A. Ground Substance


Ground substance is semi-fluid to thick gel; it can be calcified, hardening also.


It occupies space between cells and fibres in connective tissue.


A ground substance such as water, salts, and other molecules substance contained mainly-

1. Proteoglycans

2. Glycoprotein

 

Function of Ground Substance

 

1. Support cells and bind them together

2. Media for exchange of substances capillaries and tissue cell

3.  Barrier against harmful substance

4. Act as lubricants

5. Store water

6. Shock absorber

7. Proliferation of tissues

8. Medium for intercellular exchange

9. Development, movement and metabolism of tissue

 

B. Protein Fibres

 

Protein fibres provide strength and support.

Protein fibers in connective tissue have three groups-

 

1. Collagen Fibers


2. Reticular Fibers


3. Elastic Fibers

 

1. Collagen Fibers

 

Collagen fibers are synthesized by connective tissue fibroblasts. It is composed of collagen, elastic fiber, and protein.


Collagen fibers are thick, strong, flexible, and resist stretch, it provides rigid support as well as elasticity.

 

Location

 

1. Bone

2. Cartilage

3. Tendons

 4. Ligaments

5. Dermis

 

Function

 

1. Fibres add strength to connective tissue.

2. Support and protect organs.

3. Fibres connect muscles to bones and bones to bones.

 

Collagen Fibres Types

 

1. Collagen-I; found in bones, tendons, organs

2. Collagen II; found mainly in cartilage

3. Collagen-III; found mainly in reticular fibres

4. Collagen-IV; found in the basement membrane of cell membranes

5. Collagen-V; found in nails, hair

 

 

 2. Reticular fibre

 

Reticular fibre in connective tissue is composed of type-III collagen secreted by reticular cells.  It is produced by testicular cell fibroblasts.


Reticular fibers is net-like not elastic highly branched fibre, it crosslink to form a fine meshwork.

 

 Location


1. Fat cells

2. Nerve fibre

3. Skeletal and smooth muscle cell

 

Function


1. Provide support, form network around soft organ – Spleen, Lymph node, Bone marrow

2. Help to form baseline membrane.

 

3. Elastic Fibre

 

Elastic fibre is stretched easily when they are pulled and returns to its original state when force is removed.

 

Location


1. Skin

2. Blood vessel

3. Lung

 

 Function


1. Give resilience to stretch or recoil stretch easily.

2. Stretch and recoil

 


2. Connective Tissue Cells

 

Specialized cells of connective tissue produce extracellular material.


1. Blasts

 

Produce the matrix; water matrix.

For example- Osteoblasts; cell that from bone

 

2. Cytes

 

Mature cells, it maintains a matrix.

For example- Osteocytes; maintain bone

 

3. Clasts


Cells break down for remodeling.

For example- Osteoclasts; break bone matrix.


 

Based on Ability- 3 Types of Connective Tissue

 

1. Fixed cells


2. Wandering cells


3. Fat cells


 

1. Fixed Cells


a. Fibroblasts


Cell secretes fibres and ground substance of extracellular matrix. It play important role in wound healing.

 

Responsible for-


1. Cartilage formation (chondroblasts)

2. Osteoclasts

 

 b. Fibrocytes (Reticular cell)

 

Reticular cell produces reticular fibres and surrounds fibres with their cytoplasm.

 


2. Wandering Cells

 

Wandering cells or transient cells are found in connective tissue but are not fixed in place. They provide protection and repair.


For example, Leukocytes (White blood cells), Plasma cell; B-cells, mast cells, lymphocytes, macrophages


 

3. Fat cells or Adipocytes or Adipose cells

 

Fat cells store energy in form of fat.

 

Location


Found an around organ-

Kidney, Heart, Deep to skin

 

Get details on what is tissue in the body and what are types of tissue?



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