Platelets/Thrombocytopoiesis
Process of formation of platelets is called thrombocytopoiesis.
They originate from hemocytoblasts in bone marrow.
Formation of platelets takes about 10 days, newly formed platelets spend about 24-36 hours in spleen before being released into circulation.
The span of platelets is 7- 10 days. About 10% of platelets are utilized daily for minor hemorrhage and rest not used in process of hemostasis are destroyed by macrophages, mainly in the spleen.
Thrombocytopoiesis
Stem cell
Hemocytoblast in bone marrow
Megakayoblast
Promegakaryocytes
Megakaryocyte breakup
Platelets
Blood stream
(Formtion of platelets)
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