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Prolactin

 Prolactin

Prolactin hormone secreted by lactotrophs of anterior pituitary which is secreted during pregnancy to prepare the breasts for lactation (milk production) after child birth.

The blood level of prolactin is stimulated by prolactin releasing hormone (PRH) released from Hypothalamus.

Function

In female; 

To stimulate milk production by breast.

Regulation of Secretion

Prolactin inhibiting hormone PIH) "dopamine" prevent prolactin secretion.

Decrease dopamine secretion leads to increase prolactin release.

Prolactin together with Oestrogen, corticosteroid, insulin and thyroxine, is involved in initiating and maintaining lactation.

Prolactin secretion raised during period of sleep.

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