Cancer Genetics
Class of diseases in which a group of cell display uncontrolled growth, invasion (destroy adjacent tissue) and metastasis (spread to other location in body via lymph or blood).
Gene ------- Mutation ------- Cancer
Gene Mutation
1. Inherited gene mutation
It present in egg or sperm cell that formed child.
2. Acquired gene mutation
Acquired (somatic) mutation doesn't come from a parent, but acquired sometimes later.
Tumor Suppressor gene
Keep cell under control by slowing down.
Oncogene
Gene that has potential to cause cancer.
Classification of Cancer
Germ cell tumor (totipotent cell)
Carcinoma (epithelial cell)
Sarcoma (connective tissue or mesenchymal cell)
Blastic tumor (immature and embryonic tissue)
Lymphoma; hematopoietic (blood forming cells).
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