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Cell Nucleus - Structure, Function , Nuclear Pore, Nucleolus

Nucleus/ Nuclei

 

The nucleus is a storehouse of genes, the brain of cells, and the largest cell organelle. The nucleus contains genetic material in the form of RNA/DNA, thus playing an important role in the transmission of genetic material from one organism to another. It contains hereditary information.

 

The nucleus stores the cell's hereditary material or genetic material of the cell (DNA), which contains hereditary units called genes. Its controls, coordinates, and regulates all cellular activities within and outside the cell that’s why it is called the control center of the cell.  

 

Eukaryotic cells have a true nucleus, the nucleus is defined well-organized organelle containing DNA and is surrounded by a nuclear membrane.

 

Know here the structure of golgi apparatus and endoplasmic reticulum.

 

 

 

Structure of Cell Nucleus

 

 

 

Nucleus and Its Parts

 

The nucleus consists of - 

 

1. Nucleoplasm

2. Nucleolus

3. Nuclear Pore

4. Nuclear Envelope/ Nuclear Membrane

 

 

 

1. Nucleoplasm

 

It contains nucleosides (responsible for encoding, transmitting, and expressing genetic information), nucleotides (building blocks of nucleic acid; DNA and RNA), enzymes, nucleoprotein (protein associated with nucleic acids), and minerals, etc.


The nucleus stores chromatin (DNA and proteins) in a gel-like substance called, nucleoplasm. Chromatin is a substance within a chromosome consisting of DNA (deoxyribonucleic acid) and protein.


Chromatin contains most of the cellular DNA, in association with basic histone protein. Histone is a protein that provides structural support to a chromosome, giving a more compact shape to the chromosome.

 

 

2. Nucleolus

 

The spherical nucleolus is an organelle, a condensed region of chromatin in the nucleus, plays a key role in the transcription (DNA into RNA) and occurs processing of ribosomal RNA (rRNA).


Nucleoli or nucleolus are rich in RNA (Ribonucleic acid), aggregation of protein (construction of ribosome), RNA, and DNA. The nucleolus is a site where ribosome synthesis occurs.


The nucleolus's primary function is ribosomal RNA (rRNA) synthesis and ribosome biogenesis.


The nucleolus disappears during cell division. During cell division, the chromatin is organized into a small thread-like structure called a chromosome. The human somatic cell (cell except for sperm and egg cell) contains 23 pairs of chromosomes. The egg and sperm cells have only 23 chromosomes each.

 

 

3. Nuclear Pore 

 

A nuclear envelope or nuclear membrane contains many minute opening called nuclear pore which allows the exchange of material between the nucleus and cytoplasm.


Nuclear Pore connects the nucleoplasm (nucleus) with the cytoplasm.

 

 4. Nuclear Envelope 

 

It is a bilayered membrane separated by perinuclear space, bound the nucleus from outside, and separates the nucleus from the cytoplasm. The outer layer is connected with the endoplasmic reticulum.

 

 

Functions of Nucleus

 

 

Key functions are-

 

1. Nucleus controls and regulates the activities of the cell, it controls the metabolic activities of cells.

 

2. It carries the genes that contain the hereditary information and controls gene expression and mediates the replication of DNA during the cell cycle.

 

3. It controls and coordinates the direct many cellular structures, and cell activities, which include growth, metabolism, protein synthesis, and reproduction (cell division) mean it controls cell division.  So, it is called the brain of cells.

 

4. It contains genetic material in the form of DNA/ RNA and plays an important role in transmission (transferring).

 

5. All the RNA; messenger RNA (mRNA), ribosomal RNA (rRNA), and transfer RNA (tRNA) needed for the cell because they are directly involved in protein synthesis are synthesized in the nucleus. Without a nucleus, a cell can neither survive, nor show specialized activity.

 

6. It is the control center of the cells.

 

7. It controls replication (DNA Synthesis), transcription( RNA Synthesis), and translation (protein synthesis).  

 

8. DNA and RNA polymerase enzymes are markers of the nucleus.


9. It is involved in the production of various enzymes.

 

 

Check out here what is centrosome and centriole.

 

 

 

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